The global acne drugs market size is expected to reach USD 5.9 billion by 2025, according to a new report by Grand View Research, Inc., registering a 4.2% CAGR during the forecast period. Several factors such as emergence of biologics, unhealthy lifestyle, and rising disease incidence are anticipated to drive the market.
Acne
vulgaris is one of the most common dermatological disorders, affecting 9.4%
people worldwide. Although the condition can affect people of all ages, it is
most prevalent among teenagers. It has been found that the condition is
prevalent in more than 85.0% people between the ages of 12 and 25. Acne can
appear in forms ranging from comedones to cystic lesions, depending on its
severity.
Retinoids
and antibiotics remain the mainstays of acne treatment. Retinoids led the
therapeutic classes in 2017, and it is expected to continue this trend through
2025. The therapeutic landscape is witnessing a shift toward combination
treatment due to higher efficacy, convenient dosing, and fewer adverse effects.
By
mode of administration, topical drugs currently dominate the market. Severe
cases see the use of systemic medications such as oral antibiotics, hormonal
agents, or other drugs. However, emergence of biologics (Gevokizumab and
RA-18C3) will fuel the injectable route of administration. Biologics offer
improved clinical advantage over conventional topical treatments since they
target inflammatory mechanisms with disease modifying ability.
Discontinuation
or termination of key pipeline candidates on account of unsuccessful clinical
trials is a major restraint this market faces. Upon launch, Olumacostat
glasaretil (Dermira; topical lipid synthesis inhibitor) was expected to be the
first topical anti-acne drug with isotretinoin-like results without significant
side effects. However, the drug failed to meet clinical endpoints, leading to
discontinuation in March 2018. Similarly, SNA-001 (Sienna; silver nanoparticles
solution) was deemed unsuccessful in two key trials wherein it was tested in
conjunction with 810nm and 1064nm lasers in July 2018. Thesan withdrew TSN2898
from Phase II trials due to drug unavailability. Xenon discontinued development
of XEN801 after the drug failed Phase II clinical trials.
Despite
being one of the most common dermatological diseases in the world, innovation
in acne treatment has been rather limited over the past decade. Drug companies
are currently exploring novel treatment approaches including stearoyl CoA
desaturase inhibition, melanocortin receptor antagonism, and anti-IL-1
monoclonal antibodies. Impending launch of late-stage pipeline products
indicate a promising future for the global acne drugs market.
Full Research Report On Acne Drugs Market Visit Here:
https://www.grandviewresearch.com/industry-analysis/acne-drugs-market
Further key
findings from the report suggest:
- By type, inflammatory acne
captured more than 50.0% of the market in 2017. Comedonal acne were ranked
second-largest, among other types
- On the basis of therapeutic
class, retinoids led the market in 2017, followed by antibiotics. This
trend is likely to continue through 2025
- The treatment paradigm is
shifting toward combination therapies and biologics. Combination products
are gaining traction due to higher efficacy, convenient dosing, and fewer
adverse effects
- Topical products dominated
the treatment landscape, based on mode of administration. However,
introduction of biologics is likely to result in the growth of the
injectables segment
- U.S. dominated the major
markets and is projected to maintain its lead through 2025, owing to
rising disease incidence and ease of access to anti-acne products
- Allergan, Bayer, Galderma,
Stiefel, and Valeant are some key players operating in this market.
Valeant is projected to lead the market in 2025 due to higher adoption of
Retin-A micro as well as anticipated launch of pipeline candidates.
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Grand View Research has segmented
the global acne drugs market based on type, therapeutic class, mode of
administration, and country:
Acne Drugs Type
Outlook (Revenue, USD Million, 2017 - 2025)
- Comedonal
- Inflammatory
- Cystic
- Post-surgical/Wound
Acne Drugs
Therapeutic Class Outlook (Revenue, USD Million, 2017 - 2025)
- Retinoid
- Antibiotic
- Hormonal Agent
- Combination
- Others
Acne Drugs Mode of
Administration Outlook (Revenue, USD Million, 2017 - 2025)
- Topical
- Oral
- Injectable
Acne Drugs Country
Outlook (Revenue, USD Million, 2017 - 2025)
- U.S.
- U.K.
- Germany
- Spain
- France
- Italy
- Japan
About Grand View Research
Grand
View Research, Inc. is a U.S. based market research and consulting company,
registered in the State of California and headquartered in San Francisco. The
company provides syndicated research reports, customized research reports, and
consulting services. To help clients make informed business decisions, we offer
market intelligence studies ensuring relevant and fact-based research across a
range of industries, from technology to chemicals, materials and healthcare.
For more info visit @ https://www.grandviewresearch.com